Low Bone Mass and Klinefelter Syndrome

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Low bone mass in Ehlers-Danlos syndrome.

A 14-year-old girl with type-III Ehlers-Danlos syndrome (EDS) underwent a dual energy X-ray absorptiometry (DXA) evaluation of the bone mineral density (BMD) in the scoliotic lumbar spine (L-spine), which measured 0.464 g/ cm (T-score: -5.3, Z-score: -4.23) (Picture 1). The BMD was found to be 0.230 g/cm (T-score: -4.5) in the deformed distal forearm and 0.181 g/cm (T-score: -4.1) in the ultrad...

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Bone Mineral Status in Children and Adolescents with Klinefelter Syndrome

Objective. Klinefelter syndrome (KS) has long-term consequences on bone health. However, studies regarding bone status and metabolism during childhood and adolescence are very rare. Patients. This cross-sectional study involved 40 (mean age: 13.7 ± 3.8 years) KS children and adolescents and 80 age-matched healthy subjects. For both patient and control groups, we evaluated serum levels of ionise...

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Klinefelter syndrome

Some males with Klinefelter syndrome have the extra X chromosome only in some of their cells (mosaic Klinefelter syndrome). In addition, 46,XX males also exist and it is caused by translocation of Y material including sex determining region (SRY) to the X chromosome during paternal meiosis. Formal cytogenetic analysis is necessary to make a definite diagnosis, and more obvious differences in ph...

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Klinefelter syndrome

Some males with Klinefelter syndrome have the extra X chromosome only in some of their cells (mosaic Klinefelter syndrome). In addition, 46,XX males also exist and it is caused by translocation of Y material including sex determining region (SRY) to the X chromosome during paternal meiosis. Formal cytogenetic analysis is necessary to make a definite diagnosis, and more obvious differences in ph...

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Klinefelter syndrome

Some males with Klinefelter syndrome have the extra X chromosome only in some of their cells (mosaic Klinefelter syndrome). In addition, 46,XX males also exist and it is caused by translocation of Y material including sex determining region (SRY) to the X chromosome during paternal meiosis. Formal cytogenetic analysis is necessary to make a definite diagnosis, and more obvious differences in ph...

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ژورنال

عنوان ژورنال: Indian Journal of Endocrinology and Metabolism

سال: 2019

ISSN: 2230-8210

DOI: 10.4103/ijem.ijem_657_18